Deck · MCAT

Biochemistry

Amino acids and proteins, enzyme kinetics and regulation, metabolism and bioenergetics, and the molecular biology of the gene for the MCAT.

266 cards · audited · SM-2 spaced repetition

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Included with the full MCAT program — 8 decks, 1,519 cards.

Sample cards

1

What is the general structure of a standard (proteinogenic) amino acid?

A central α-carbon bonded to four groups: an amino group (-NH3+), a carboxyl group (-COO-), a hydrogen atom, and a variable R-group (side chain).

2

What is the absolute configuration of the 19 chiral standard amino acids found in proteins?

L-configuration (S in the CIP/R-S system, except L-cysteine, which is R because sulfur raises the side chain's priority).

3

Why is an amino acid called a dipolar ion (zwitterion) at physiological pH?

At pH ~7 the carboxyl group is deprotonated (-COO-) and the amino group is protonated (-NH3+), so the molecule carries both a negative and a positive charge but is net neutral.

4

Which standard amino acids have nonpolar, aliphatic side chains?

Glycine, alanine, valine, leucine, isoleucine, methionine, and proline (proline's side chain forms a ring with the backbone N).

5

Which standard amino acids are aromatic?

Phenylalanine, tyrosine, and tryptophan. (Histidine has an aromatic imidazole ring but is usually classed as basic/positively charged.)

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