Deck · USMLE Step 1
Reproductive
Reproductive embryology and endocrine physiology, male and female pathology, breast disease, pregnancy and placental disorders, STIs, and reproductive pharmacology.
95 cards · audited · SM-2 spaced repetition
Included with the full USMLE Step 1 program — 14 decks, 1,546 cards.
Sample cards
What is the genetic and gonadal basis of the default (indifferent) pathway of sexual differentiation?
Without a Y chromosome (and its SRY gene), the indifferent gonad develops into an ovary and the default phenotype is female. SRY drives testis development.
What does SRY induce, and what hormones do the resulting cells secrete?
SRY induces testis development: Sertoli cells secrete Müllerian inhibitory factor (MIF/AMH) and Leydig cells secrete testosterone.
What do the Müllerian (paramesonephric) ducts develop into in females?
Fallopian tubes, uterus, cervix, and the upper one-third of the vagina.
What do the Wolffian (mesonephric) ducts develop into, and what drives this?
Driven by testosterone, the Wolffian ducts form the seminal vesicles, epididymis, ejaculatory duct, and ductus deferens (SEED).
What is the role of dihydrotestosterone (DHT) in male genital development?
DHT (converted from testosterone by 5α-reductase) drives development of the prostate, penis, scrotum, and male external genitalia.
Showing 5 of 95 cards. Unlock the program to study them all.
More in USMLE Step 1
Master reproductive — and the rest of USMLE Step 1.
One program. 1,546 audited cards across 14 decks.